1-ISOPROPYL-3-(TRIFLUOROMETHYL)PYRAZOLE-5-BORONIC ACID

1-ISOPROPYL-3-(TRIFLUOROMETHYL)PYRAZOLE-5-BORONIC ACID - Names and Identifiers

Name	[1-Isopropyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]boronic acid
Synonyms	1-isopropyl-3-(trifluoroMethyl)pyrazole-5-boronic acid [1-Isopropyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]boronic acid (1-Isopropyl-3-(trifluoroMethyl)-1H-pyrazol-5-yl)boronic acid Boronic acid, B-[1-(1-methylethyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl]-
CAS	1361380-69-9
InChI	InChI=1S/C7H10BF3N2O2/c1-4(2)13-6(8(14)15)3-5(12-13)7(9,10)11/h3-4,14-15H,1-2H3

1-ISOPROPYL-3-(TRIFLUOROMETHYL)PYRAZOLE-5-BORONIC ACID - Physico-chemical Properties

Molecular Formula	C7H10BF3N2O2
Molar Mass	221.97
Density	1.4±0.1 g/cm3
Boling Point	314.8±52.0 °C at 760 mmHg
Flash Point	144.2±30.7 °C
Vapor Presure	0.0±0.7 mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.467
MDL	MFCD24448764

1-ISOPROPYL-3-(TRIFLUOROMETHYL)PYRAZOLE-5-BORONIC ACID - Introduction

1-Isopropyl-(trifluoromethyl) pyrazole-5-boronic acid is an organoboron compound with the chemical formula C9H14BF3N2O2. It has the following properties:

1. Appearance: 1-isopropyl-(trifluoromethyl) pyrazole-5-boronic acid is a white crystalline solid.
2. Melting point: about 100-120°C.
3. Solubility: Soluble in water and organic solvents.
4. Stability: Stable under normal conditions, but decomposition may occur at high temperature or in contact with organic matter.

This substance has a wide range of applications in organic synthesis, mainly as a catalyst and reagent. Specific uses include:

1. Synthesis of functional materials: It can be used to synthesize a variety of organic functional materials containing trifluoromethyl, such as polymers and conjugated systems.
2. metal organic chemistry: as an electron-rich boron reagent, it can be used in the synthesis and conversion of metal organic compounds.
3. Catalyst: It can be used as a catalyst for organic synthesis reactions, such as oxidation reactions, carbonylation reactions, etc.

The method of preparing 1-isopropyl-(trifluoromethyl) pyrazole-5-boronic acid can be carried out by the following steps:

1. In an appropriate solvent, 1-isopropylpyrazole is reacted with trifluoromethyl borate to generate the target product. The reaction conditions can be selected according to the specific conditions, such as temperature, reaction time, etc.

When using 1-isopropyl-(trifluoromethyl) pyrazole-5-boronic acid, the following safety information should be noted:

1. Irritating to skin and eyes, please avoid contact.
2. Please wear appropriate personal protective equipment during operation, including laboratory gloves, protective glasses and protective clothing.
3. Avoid inhaling the dust or vapor of the compound, and operate in a well-ventilated place.
4. should be stored in a dry, cool place, and with flammable and oxidant stored separately.

Last Update：2024-04-10 22:29:15